Spyre Therapeutics Inc (SYRE) financials

NASDAQ · Health Care

$96.56 -2.43% Close Oct 30, 2026 Live

Spyre Therapeutics revenue and earnings by year

Spyre Therapeutics's revenue was $886,000 in the fiscal year to December 31, 2023, down 62.0% from the year before. Net income was -$339 million, -38238.1% of revenue. Since the fiscal year to December 31, 2016, revenue has shrunk 21.0% a year on average.

RevenueNet income
-$200M$0
201620172018202120222023

Fiscal years, each labelled by the calendar year it ended in.

Income statement, the last 6 fiscal years

In millions of US dollars except per-share figures. Each column is a fiscal year, named by the month it ended.
Fiscal year toDec 2023Dec 2022Dec 2021Dec 2018Dec 2017Dec 2016
Revenue1219455
Revenue growth-62.0%-87.6%382.0%-25.3%12.5%—
Operating income-242-85-66-45-28-22
Operating margin-27348.0%-3640.2%-350.3%-1169.3%-531.7%-473.3%
Net income-339-84-66-44-27-22
Net margin-38238.1%-3598.8%-351.1%-1140.6%-523.3%-468.8%
Diluted EPS-$49.12-$24.86————
Free cash flow-100-80-54-33-25-19

Diluted EPS is stated in today's shares (adjusted for every split since). Quarterly statements and the income statement as a flow chart are in the app: open SYRE in Markets.

See also: SYRE returns

No forecast, no recommendation. This page describes Spyre Therapeutics Inc from published data; it is not advice to buy, sell or hold any security.

Figures as of the close on Oct 30, 2026 unless a row says otherwise. Prices are split adjusted; returns include dividends reinvested. Data may be delayed. See the disclaimer and how TrendArc works.