Large US-listed stocks with the biggest one-year declines
At the close on October 30, 2026, 159 US-listed companies had a market value of $10 billion or more and a negative total return over the past year (the price change with dividends reinvested). The first 20 are listed, largest one-year decline first.
The first 20 of 159
| # | Company | Sector | Price | 1 year | P/E | Market value |
|---|---|---|---|---|---|---|
| 1 | Alnylam PharmaceuticalsALNY | Health Care | $165.00 | -63.3% | 41.5 | $22.1B |
| 2 | AppLovinAPP | Information Technology | $228.50 | -63.2% | 17.6 | $76.8B |
| 3 | Boston ScientificBSX | Health Care | $41.98 | -58.3% | 17.0 | $62.4B |
| 4 | CoreWeaveCRWV | Information Technology | $54.87 | -58.1% | — | $29.9B |
| 5 | CoStar GroupCSGP | Real Estate | $30.17 | -56.7% | 67.0 | $12.2B |
| 6 | Coinbase GlobalCOIN | Financials | $143.54 | -56.3% | — | $37.9B |
| 7 | Fair IsaacFICO | Information Technology | $711.23 | -55.1% | 20.6 | $16.5B |
| 8 | InsuletPODD | Health Care | $149.68 | -52.0% | 28.1 | $10.4B |
| 9 | Charter CommunicationsCHTR | Communication Services | $111.49 | -51.7% | 2.9 | $13.7B |
| 10 | IonQIONQ | Information Technology | $30.04 | -50.1% | — | $11.2B |
| 11 | MicroStrategyMSTR | Information Technology | $130.51 | -48.7% | — | $45.7B |
| 12 | OracleORCL | Information Technology | $130.67 | -48.5% | 20.5 | $376B |
| 13 | IntuitINTU | Information Technology | $341.09 | -47.3% | 20.7 | $93.3B |
| 14 | NRG EnergyNRG | Utilities | $96.06 | -43.8% | 25.0 | $20.3B |
| 15 | ServiceNowNOW | Information Technology | $105.12 | -43.8% | 75.6 | $109B |
| 16 | ZoetisZTS | Health Care | $79.72 | -43.2% | 13.0 | $33.4B |
| 17 | Alibaba Group HoldingBABA | Communication Services | $98.04 | -43.1% | 23.7 | $228B |
| 18 | NetflixNFLX | Communication Services | $62.08 | -43.0% | 17.9 | $262B |
| 19 | SoFi TechnologiesSOFI | Financials | $16.76 | -42.3% | 34.2 | $21.5B |
| 20 | PDD HoldingsPDD | Information Technology | $78.61 | -42.2% | 8.8 | $110B |
This page shows the first 20 matches.
How this list is built
A company is on this list when, at the close named above, it had a market value of $10 billion or more and a negative total return over the past year (the price change with dividends reinvested). The test runs over the 2,300+ US-listed stocks that have a page on TrendArc: stocks listed on the NYSE, Nasdaq, NYSE American or Cboe, one line per company where a company has more than one share class.
Prices are closing prices adjusted for splits, and the 52-week high and low are the highest and lowest of those closes over the past 52 weeks. The P/E divides the share price by diluted earnings per share over the last twelve months; the forward P/E divides it by the earnings analysts expect over the next twelve. The one-year return is the change in price with dividends reinvested.
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No forecast, no recommendation. A list made by a fixed filter is not advice to buy, sell or hold any security, and a company's place on it says nothing about where its price goes next.