Septerna Inc (SEPN) returns
$44.00 -2.72% Close Oct 30, 2026 Live
Septerna returns over 1 year
$1,000 invested in Septerna one year ago was worth $2,047 at the close on October 30, 2026, with dividends reinvested. The same $1,000 in the S&P 500 (SPY) became $1,124.
SEPN, $10,000 investedS&P 500 (SPY)
$5,000$10,000$15,000$20,000
20252026
Total return by period
| Period | Total return | A year, on average | $1,000 became | S&P 500 (SPY) |
|---|---|---|---|---|
| 1 month | +12.4% | — | $1,124 | -0.9% |
| 3 months | +25.1% | — | $1,251 | +2.1% |
| Year to date | +57.8% | — | $1,578 | +11.7% |
| 1 year | +104.7% | — | $2,047 | +12.4% |
Septerna return by calendar year
| Year | SEPN | S&P 500 (SPY) | Difference |
|---|---|---|---|
| 2026 to date | +57.8% | +11.7% | +46.1% |
| 2025 | +21.7% | +17.7% | +4.0% |
Past returns do not predict future returns. Returns are computed from our daily closes, adjusted for splits and with dividends reinvested on their ex-dates; taxes and trading costs are left out.
See also: SEPN financials
No forecast, no recommendation. This page describes Septerna Inc from published data; it is not advice to buy, sell or hold any security.
Figures as of the close on Oct 30, 2026 unless a row says otherwise. Prices are split adjusted; returns include dividends reinvested. Data may be delayed. See the disclaimer and how TrendArc works.